The genome browser provides five tracks.
Shows C. elegans genes.
Shows transcripts of genes.
The UCSC genome browser provides a good explanation of the phyloP and phastCons tracks and how to interpret them.
phyloP (phylogenetic P-values) are designed to detect lineage-specific selection. Positive scores indicate conserved sites (slower evolution than expected under drift) whereas negative scores indicate acceleration (faster evolution than expected under drift).
- Caenorhabditis elegans
- Caenorhabditis brenneri
- Caenorhabditis japonica
- Caenorhabditis remanei
- Caenorhabditis briggsae
- Strongyloides ratti
- Onchocerca volvulus
- Brugia malayi
phastCons scores range from 0-1 and represent the probability that each nucleotide belongs to a conserved element.
The variants track shows variation across the species for all isotypes sequenced. Variants are colored according to the legend:
There are three tracks (LOW, MODERATE, HIGH) that can be used to show variants and their predicted impacts as annotated by SnpEff. The tracks are color coded based on severity as follows:
These annotations can be used to assess what functional affects a given variant may have and are grouped into LOW, MODERATE, and HIGH impact variants. More information on variant predictions is available on the Variant Prediction page.
Strain Specific Tracks
The variants for individual isotypes can be viewed by selecting tracks from the strain list:
Isotypes can also be filtered using the search box. Like the variant track for the entire species, reference and alternate genotypes are colored as follows:
Missing genotypes are excluded.
Variants displayed on the genome browser are 'soft-filtered', meaning that in some cases they are poor quality. However, we still report them but using a different set of colors to indicate that they should be interpretted carefully. When you hover your mouse over filtered variants on the browser page, the name of the filter will appear as a tooltip.
Examples are listed below
DL238 - A passing alternative variant
QX1211 - A reference variant
XZ1516 - An alternative variant
JU1218 - A heterozygous variant