telomere-length telomere-resids

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  • Release: 20170531
  • Availabity: Public

Phenotype

Histogram representation of your phenotype Your phenotype is significantly associated with genetic variation present in the C. elegans population!

Manhattan Plot

Manhattan Plot

A genome-wide representation of the association between variation in the C. elegans population and your phenotype. The x-axis corresponds to genomic position with chromosome number indicated as a roman numeral above each box. Dots represent single-nucleotide variants (SNV) present in the C. elegans population. The y-axis corresponds to the level of significance for the association test. Blue dots represent SNVs that are above the defined significance threshold, which is the thick gray line. Red boxes surrounding blue dots represent the QTL genomic region of interest, which we define as plus/minus 50 SNVs from the last signifincant SNV. The default threshold for significance is the Bonferroni-corrected value and is usually around 5.5.

QTL Genomic Region of Interest

Interval Peak Position -log10p V.E.
II:10,411,984-11,168,605 II:10,781,013 5.54 10.867%
II:12,831,063-15,276,626 II:14,132,538 17.88 23.935%
The number of variants, and number of genes affected by moderate and high impact variants are in the biotype summary tables below. More information regarding the types of variants classified as Moderate or High impact is available in the help section.

Phenotype-by-Genotype


PxG Plot

Phenotypic distributions represented as box plots are split by the genotype at the most significant SNV for a given QTL. The phenotype is on the y-axis, and the genotype is on the x-axis. The chromosome and position for the plotted SNV are indicated as roman numerals above each panel. REF refers to the reference N2 genotype, and ALT refers to the alternative variant phenotype. All of the SNVs in our data set are biallelic, so only two classes for any given SNV site exist.

Linkage Disequilibrium

The Linkage Disequilibrium (LD) measure plotted is the correlation between peak markers:


D is the raw difference in frequency between the observed number of AB pairs and the expected number and A, B, a, and b refer to alleles at the two loci. An LD value of 0.8 or higher suggests that the two peak markers are not segregating randomly.


Peak Summary

Switch between peaks below.



  • Peak Interval  II:10411984-11168605
  • Peak Position  
  • Variance Explained  10.87%
Download Table
Biotype # Genes # Genes w/ variants MODIFIER + LOW + MODERATE + HIGH + # Variants
Total 250 227 214 152 149 18 6979
protein_coding 167 176 163 148 144 16 6575
pseudogene 5 7 7 1 1 1 224
lincRNA 0 39 39 3 4 1 174
snoRNA 7 4 4 0 0 0 5
miRNA 1 1 1 0 0 0 1
ncRNA 64 0 0 0 0 0 0
piRNA 4 0 0 0 0 0 0
tRNA 1 0 0 0 0 0 0
transposon_protein_coding 1 0 0 0 0 0 0
All variants are reported from the 20170531 data release regardless of which isotypes were submitted for the mapping. This is in contrast to newer reports which report genes and variants among only those isotypes that were submitted for a given trait.

Variants

The table below lists variants, their predicted effects, and their correlation with the phenotype. Only protein coding genes have their variants correlated with phenotype.

Download Table
Gene Name Wormbase ID Transcript CHROM:POS Biotype AA Change Annotation Impact Correlation Max. Correlation
ZK673.1 WBGene00014057 ZK673.1a II:10444945 protein_coding p.Thr132Ala missense_variant MODERATE 0.191 0.191
ZK673.1 WBGene00014057 ZK673.1b II:10444945 protein_coding p.Arg63Arg synonymous_variant LOW 0.191 0.191
nphp-1 WBGene00010898 M28.7 II:10650408 protein_coding p.Arg314Gln missense_variant MODERATE 0.191 0.191
dohh-1 WBGene00007555 C14A4.1 II:10580155 protein_coding p.Val45Ile missense_variant MODERATE 0.191 0.191
pro-1 WBGene00004185 R166.4 II:10541949 protein_coding p.Gly13Ser missense_variant MODERATE 0.191 0.191
pro-1 WBGene00004185 R166.4 II:10541171 protein_coding p.Ser115Gly missense_variant MODERATE 0.166 0.191
crn-5 WBGene00000798 C14A4.5 II:10592912 protein_coding p.Met51Leu missense_variant MODERATE 0.191 0.191
F40F8.12 WBGene00044917 F40F8.12 II:11130290 protein_coding p.Tyr4Cys missense_variant MODERATE 0.189 0.189
R03D7.8 WBGene00010992 R03D7.8 II:10955985 protein_coding p.Gln163Leu missense_variant MODERATE 0.189 0.189
R03D7.2 WBGene00010989 R03D7.2 II:10933871 protein_coding p.Thr368Ile missense_variant MODERATE 0.189 0.189
R03D7.2 WBGene00010989 R03D7.2 II:10934250 protein_coding p.Ser242Pro missense_variant MODERATE 0.189 0.189
metr-1 WBGene00010988 R03D7.1 II:10926604 protein_coding p.Ala14Val missense_variant MODERATE 0.189 0.189
metr-1 WBGene00010988 R03D7.1 II:10929238 protein_coding p.Glu750Gln missense_variant MODERATE -0.141 0.189
M28.10 WBGene00010901 M28.10.1 II:10648519 protein_coding p.Val250Ala missense_variant MODERATE 0.183 0.183
M28.10 WBGene00010901 M28.10.2 II:10648519 protein_coding p.Val250Ala missense_variant MODERATE 0.183 0.183
M28.10 WBGene00010901 M28.10.1 II:10647762 protein_coding p.Asp63Asn missense_variant MODERATE 0.154 0.183
M28.10 WBGene00010901 M28.10.2 II:10647762 protein_coding p.Asp63Asn missense_variant MODERATE 0.154 0.183
M28.10 WBGene00010901 M28.10.1 II:10647798 protein_coding p.Cys75Ser missense_variant MODERATE 0.154 0.183
M28.10 WBGene00010901 M28.10.2 II:10647798 protein_coding p.Cys75Ser missense_variant MODERATE 0.154 0.183
M28.9 WBGene00010900 M28.9.1 II:10641216 protein_coding p.Val319Ala missense_variant MODERATE 0.18 0.18
M28.9 WBGene00010900 M28.9.2 II:10641216 protein_coding p.Val319Ala missense_variant MODERATE 0.18 0.18
M28.9 WBGene00010900 M28.9.1 II:10641373 protein_coding p.Gln355His missense_variant MODERATE 0.18 0.18
M28.9 WBGene00010900 M28.9.2 II:10641373 protein_coding p.Gln355His missense_variant MODERATE 0.18 0.18
M28.9 WBGene00010900 M28.9.1 II:10640665 protein_coding p.Thr228Ile missense_variant MODERATE 0.146 0.18
M28.9 WBGene00010900 M28.9.2 II:10640665 protein_coding p.Thr228Ile missense_variant MODERATE 0.146 0.18
M28.8 WBGene00010899 M28.8 II:10629865 protein_coding p.Glu282Lys missense_variant MODERATE 0.18 0.18
M28.2 WBGene00010894 M28.2 II:10634564 protein_coding p.Ile288Met missense_variant MODERATE 0.18 0.18
M28.2 WBGene00010894 M28.2 II:10638202 protein_coding p.Tyr519His missense_variant MODERATE 0.147 0.18
M28.2 WBGene00010894 M28.2 II:10638677 protein_coding p.Asn645Asp missense_variant MODERATE 0.147 0.18
M28.2 WBGene00010894 M28.2 II:10639023 protein_coding p.Thr653Ala missense_variant MODERATE 0.147 0.18
ptb-1 WBGene00004207 D2089.4a II:10689187 protein_coding p.Ala564Thr missense_variant MODERATE 0.167 0.167
ptb-1 WBGene00004207 D2089.4b.1 II:10689187 protein_coding p.Ala402Thr missense_variant MODERATE 0.167 0.167
ptb-1 WBGene00004207 D2089.4b.2 II:10689187 protein_coding p.Ala402Thr missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4d II:10748291 protein_coding p.Pro1593Ser missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4i II:10748291 protein_coding p.Pro82Ser missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4h II:10748291 protein_coding p.Pro511Ser missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4c II:10748291 protein_coding p.Pro1304Ser missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4e II:10748291 protein_coding p.Pro1286Ser missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4g II:10748291 protein_coding p.Pro1286Ser missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4a II:10748291 protein_coding p.Pro1495Ser missense_variant MODERATE 0.167 0.167
mpz-1 WBGene00003404 C52A11.4f II:10748291 protein_coding p.Pro1473Ser missense_variant MODERATE 0.167 0.167
gbh-1 WBGene00001522 D2089.5 II:10692216 protein_coding p.Arg187Lys missense_variant MODERATE 0.167 0.167
bli-1 WBGene00000251 C09G5.6.1 II:10711589 protein_coding p.Asn829Asp missense_variant MODERATE 0.167 0.167
bli-1 WBGene00000251 C09G5.6.2 II:10711589 protein_coding p.Asn829Asp missense_variant MODERATE 0.167 0.167
R166.3 WBGene00011303 R166.3 II:10537949 protein_coding p.His194Tyr missense_variant MODERATE 0.166 0.166
E04D5.2 WBGene00008481 E04D5.2 II:10420367 protein_coding p.Ser306Thr missense_variant MODERATE 0.166 0.166
mab-10 WBGene00003107 R166.1a II:10531796 protein_coding p.Gly286Glu missense_variant MODERATE 0.166 0.166
mab-10 WBGene00003107 R166.1a II:10531990 protein_coding p.Ser351Ala missense_variant MODERATE 0.166 0.166
ect-2 WBGene00002297 T19E10.1b.1 II:10779962 protein_coding p.Tyr775Asn missense_variant MODERATE 0.166 0.166
ect-2 WBGene00002297 T19E10.1a.2 II:10779962 protein_coding p.Tyr775Asn missense_variant MODERATE 0.166 0.166
ect-2 WBGene00002297 T19E10.1b.2 II:10779962 protein_coding p.Tyr775Asn missense_variant MODERATE 0.166 0.166
ect-2 WBGene00002297 T19E10.1a.1 II:10779962 protein_coding p.Tyr775Asn missense_variant MODERATE 0.166 0.166
M28.4 WBGene00010895 M28.4 II:10645134 protein_coding p.Thr295Ile missense_variant MODERATE 0.154 0.154
M28.4 WBGene00010895 M28.4 II:10645823 protein_coding p.Ser438Pro missense_variant MODERATE 0.154 0.154
M28.4 WBGene00010895 M28.4 II:10643785 protein_coding p.Gln28Leu missense_variant MODERATE 0.147 0.154
M28.4 WBGene00010895 M28.4 II:10645722 protein_coding p.Leu404Ser missense_variant MODERATE 0.147 0.154
M28.4 WBGene00010895 M28.4 II:10644107 protein_coding p.Leu120Gln missense_variant MODERATE 0.146 0.154
srv-2 WBGene00005713 C14A4.15 II:10600950 protein_coding p.Phe234Cys missense_variant MODERATE 0.145 0.145
sra-12 WBGene00005038 F44F4.7 II:10902863 protein_coding p.Leu293Phe missense_variant MODERATE -0.142 0.142
C06A1.7 WBGene00044235 C06A1.7 II:10565381 protein_coding p.Ser142Pro missense_variant MODERATE 0.14 0.14
C14A4.3 WBGene00007556 C14A4.3 II:10586742 protein_coding p.Cys394Phe missense_variant MODERATE 0.14 0.14
pqm-1 WBGene00004096 F40F8.7.1 II:11152232 protein_coding p.Leu62Phe missense_variant MODERATE -0.137 0.137
pqm-1 WBGene00004096 F40F8.7.2 II:11152232 protein_coding p.Leu62Phe missense_variant MODERATE -0.137 0.137
E04D5.4 WBGene00008483 E04D5.4a II:10442351 protein_coding p.Asn161Lys missense_variant MODERATE 0.132 0.132
E04D5.4 WBGene00008483 E04D5.4b II:10442351 protein_coding p.Ile56Lys missense_variant MODERATE 0.132 0.132


  • Peak Interval  II:12831063-15276626
  • Peak Position  
  • Variance Explained  23.94%
Download Table
Biotype # Genes # Genes w/ variants MODIFIER + LOW + MODERATE + HIGH + # Variants
Total 597 550 541 418 368 78 33983
protein_coding 391 411 402 374 354 69 32077
lincRNA 2 83 83 18 11 1 1068
pseudogene 31 38 38 20 0 7 740
antisense 0 5 5 4 3 1 74
snRNA 8 5 5 1 0 0 11
snoRNA 8 5 5 0 0 0 9
miRNA 7 3 3 1 0 0 4
asRNA 3 0 0 0 0 0 0
ncRNA 128 0 0 0 0 0 0
piRNA 10 0 0 0 0 0 0
tRNA 2 0 0 0 0 0 0
transposon_protein_coding 7 0 0 0 0 0 0
All variants are reported from the 20170531 data release regardless of which isotypes were submitted for the mapping. This is in contrast to newer reports which report genes and variants among only those isotypes that were submitted for a given trait.

Variants

The table below lists variants, their predicted effects, and their correlation with the phenotype. Only protein coding genes have their variants correlated with phenotype.

Download Table
Gene Name Wormbase ID Transcript CHROM:POS Biotype AA Change Annotation Impact Correlation Max. Correlation
srh-42 WBGene00005265 Y54G11A.15 II:14288884 protein_coding p.Phe62Tyr missense_variant MODERATE 0.389 0.389
srh-42 WBGene00005265 Y54G11A.15 II:14289014 protein_coding p.Gly19Arg missense_variant MODERATE 0.389 0.389
srh-42 WBGene00005265 Y54G11A.15 II:14288758 protein_coding p.Ala104Val missense_variant MODERATE -0.227 0.389
srh-42 WBGene00005265 Y54G11A.15 II:14288306 protein_coding p.Gln169His missense_variant MODERATE -0.209 0.389
Y54G11A.19 WBGene00235256 Y54G11A.19 II:14256782 protein_coding p.Phe33Cys missense_variant MODERATE 0.386 0.386
Y48B6A.10 WBGene00012981 Y48B6A.10 II:14215470 protein_coding p.Val74Glu missense_variant MODERATE 0.386 0.386
Y48B6A.10 WBGene00012981 Y48B6A.10 II:14215992 protein_coding p.Val181Glu missense_variant MODERATE 0.181 0.386
Y48B6A.10 WBGene00012981 Y48B6A.10 II:14216052 protein_coding p.Gly201Glu missense_variant MODERATE 0.181 0.386
K10H10.13 WBGene00194888 K10H10.13 II:14510883 protein_coding p.Tyr121His missense_variant MODERATE 0.386 0.386
Y54G11A.17 WBGene00185067 Y54G11A.17 II:14349246 protein_coding p.Leu54Ser missense_variant MODERATE 0.386 0.386
dmsr-6 WBGene00013222 Y54G11B.1.1 II:14462821 protein_coding p.Asp96Glu missense_variant MODERATE 0.386 0.386
dmsr-6 WBGene00013222 Y54G11B.1.2 II:14462821 protein_coding p.Asp96Glu missense_variant MODERATE 0.386 0.386
Y54E2A.4 WBGene00013189 Y54E2A.4a II:14755210 protein_coding p.Ala146Thr missense_variant MODERATE 0.386 0.386
Y54E2A.4 WBGene00013189 Y54E2A.4a II:14770600 protein_coding p.Thr1117Met missense_variant MODERATE -0.179 0.386
Y54E2A.4 WBGene00013189 Y54E2A.4b II:14770600 protein_coding p.Thr399Met missense_variant MODERATE -0.179 0.386
R06A4.2 WBGene00011047 R06A4.2 II:14362924 protein_coding p.Ser277Asn missense_variant MODERATE 0.386 0.386
R06A4.2 WBGene00011047 R06A4.2 II:14363980 protein_coding p.Thr598Ala missense_variant MODERATE -0.19 0.386
pot-2 WBGene00010195 F57C2.3 II:14524396 protein_coding p.Phe68Ile missense_variant MODERATE 0.386 0.386
btb-19 WBGene00010194 F57C2.2 II:14521928 protein_coding p.Ser49Leu missense_variant MODERATE 0.386 0.386
btb-20 WBGene00010193 F57C2.1 II:14523442 protein_coding p.Ser22Leu missense_variant MODERATE 0.386 0.386
btb-20 WBGene00010193 F57C2.1 II:14522867 protein_coding p.Ser181Arg missense_variant MODERATE 0.366 0.386
btb-20 WBGene00010193 F57C2.1 II:14523083 protein_coding p.Gln126Lys missense_variant MODERATE 0.366 0.386
F26H11.4 WBGene00009182 F26H11.4 II:14410198 protein_coding p.Phe326Leu missense_variant MODERATE 0.386 0.386
mltn-9 WBGene00008964 F19H8.4 II:14617721 protein_coding p.Thr273Ala missense_variant MODERATE 0.386 0.386
mltn-9 WBGene00008964 F19H8.4 II:14621834 protein_coding p.Ser646Ala missense_variant MODERATE 0.185 0.386
C13B4.1 WBGene00007545 C13B4.1a II:14472111 protein_coding p.Gly797Ser missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1c II:14472111 protein_coding p.Gly42Ser missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1b.2 II:14472111 protein_coding p.Gly797Ser missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1b.1 II:14472111 protein_coding p.Gly797Ser missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1a II:14476107 protein_coding p.Pro515Ala missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1b.2 II:14476107 protein_coding p.Pro515Ala missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1b.1 II:14476107 protein_coding p.Pro515Ala missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1a II:14478512 protein_coding p.Asp153Tyr missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1b.2 II:14478512 protein_coding p.Asp153Tyr missense_variant MODERATE 0.386 0.386
C13B4.1 WBGene00007545 C13B4.1b.1 II:14478512 protein_coding p.Asp153Tyr missense_variant MODERATE 0.386 0.386
gcy-29 WBGene00007314 C04H5.3 II:14546279 protein_coding p.Ile117Met missense_variant MODERATE 0.386 0.386
gcy-29 WBGene00007314 C04H5.3 II:14541233 protein_coding p.Glu983Lys missense_variant MODERATE 0.366 0.386
gcy-29 WBGene00007314 C04H5.3 II:14544287 protein_coding p.Asp469Gly missense_variant MODERATE 0.366 0.386
gcy-29 WBGene00007314 C04H5.3 II:14542457 protein_coding p.Val778Met missense_variant MODERATE -0.206 0.386
gcy-29 WBGene00007314 C04H5.3 II:14545408 protein_coding p.Val260Met missense_variant MODERATE -0.184 0.386
gcy-29 WBGene00007314 C04H5.3 II:14548132 protein_coding p.Lys63Asn missense_variant MODERATE -0.184 0.386
gcy-29 WBGene00007314 C04H5.3 II:14548137 protein_coding p.Glu62Lys missense_variant MODERATE -0.184 0.386
unc-52 WBGene00006787 ZC101.2e II:14656989 protein_coding p.Thr1918Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2a II:14656989 protein_coding p.Thr1918Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2c II:14656989 protein_coding p.Thr1731Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2d II:14656989 protein_coding p.Thr1825Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2f II:14656989 protein_coding p.Thr1825Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2i II:14656989 protein_coding p.Thr1632Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2j II:14656989 protein_coding p.Thr1725Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2k II:14656989 protein_coding p.Thr1732Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2l II:14656989 protein_coding p.Thr1629Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2m II:14656989 protein_coding p.Thr1819Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2n II:14656989 protein_coding p.Thr1824Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2o II:14656989 protein_coding p.Thr1918Lys missense_variant MODERATE 0.386 0.386
unc-52 WBGene00006787 ZC101.2e II:14649893 protein_coding p.Thr2797Lys missense_variant MODERATE -0.203 0.386
unc-52 WBGene00006787 ZC101.2g II:14649893 protein_coding p.Thr298Lys missense_variant MODERATE -0.203 0.386
K09E4.2 WBGene00010720 K09E4.2a II:14128119 protein_coding p.Asn546Ile missense_variant MODERATE 0.381 0.381
K09E4.2 WBGene00010720 K09E4.2b II:14128119 protein_coding p.Asn494Ile missense_variant MODERATE 0.381 0.381
K09E4.2 WBGene00010720 K09E4.2a II:14129381 protein_coding p.Gly415Asp missense_variant MODERATE 0.381 0.381
K09E4.2 WBGene00010720 K09E4.2b II:14129381 protein_coding p.Gly363Asp missense_variant MODERATE 0.381 0.381
K09E4.2 WBGene00010720 K09E4.2a II:14128014 protein_coding p.Ser581Phe missense_variant MODERATE 0.181 0.381
K09E4.2 WBGene00010720 K09E4.2b II:14128014 protein_coding p.Ser529Phe missense_variant MODERATE 0.181 0.381
ace-4 WBGene00000038 Y48B6A.7 II:14199310 protein_coding p.Pro145Thr missense_variant MODERATE 0.381 0.381
ace-4 WBGene00000038 Y48B6A.7 II:14198830 protein_coding p.Asp19Asn missense_variant MODERATE 0.367 0.381
Y54G11A.14 WBGene00013221 Y54G11A.14a II:14319964 protein_coding p.Thr393Met missense_variant MODERATE 0.372 0.372
Y54G11A.14 WBGene00013221 Y54G11A.14a II:14318316 protein_coding p.Asn53Lys missense_variant MODERATE -0.221 0.372
K10H10.7 WBGene00010763 K10H10.7 II:14507291 protein_coding p.Gly98Asp missense_variant MODERATE 0.37 0.37
C04H5.7 WBGene00007315 C04H5.7a.1 II:14538233 protein_coding p.Ser60Pro missense_variant MODERATE 0.366 0.366
C04H5.7 WBGene00007315 C04H5.7a.2 II:14538233 protein_coding p.Ser60Pro missense_variant MODERATE 0.366 0.366
C04H5.1 WBGene00007312 C04H5.1 II:14535038 protein_coding p.Ile101Val missense_variant MODERATE 0.366 0.366
Y53F4B.21 WBGene00013167 Y53F4B.21 II:15097566 protein_coding p.Ser355Thr missense_variant MODERATE 0.36 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12b II:15022676 protein_coding p.Lys387Arg missense_variant MODERATE 0.36 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12a II:15022676 protein_coding p.Lys346Arg missense_variant MODERATE 0.36 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12b II:15025554 protein_coding p.Leu716Phe missense_variant MODERATE 0.36 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12a II:15025554 protein_coding p.Leu675Phe missense_variant MODERATE 0.36 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12b II:15019322 protein_coding p.Met33Ile missense_variant MODERATE 0.318 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12a II:15019322 protein_coding p.Met33Ile missense_variant MODERATE 0.318 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12b II:15019333 protein_coding p.Ala37Gly missense_variant MODERATE 0.318 0.36
Y53F4B.12 WBGene00013159 Y53F4B.12a II:15019333 protein_coding p.Ala37Gly missense_variant MODERATE 0.318 0.36
W03H9.1 WBGene00012227 W03H9.1 II:14149723 protein_coding p.Ser106Leu missense_variant MODERATE 0.341 0.341
W03H9.1 WBGene00012227 W03H9.1 II:14149875 protein_coding p.His71Arg missense_variant MODERATE 0.341 0.341
W03H9.1 WBGene00012227 W03H9.1 II:14149998 protein_coding p.Arg45Gln missense_variant MODERATE 0.341 0.341
W03H9.1 WBGene00012227 W03H9.1 II:14148294 protein_coding p.Arg567Lys missense_variant MODERATE 0.306 0.341
W03H9.1 WBGene00012227 W03H9.1 II:14147568 protein_coding p.Thr809Ile missense_variant MODERATE 0.299 0.341
W03H9.1 WBGene00012227 W03H9.1 II:14148097 protein_coding p.Phe633Ile missense_variant MODERATE -0.192 0.341
W03H9.1 WBGene00012227 W03H9.1 II:14147734 protein_coding p.Tyr754Asp missense_variant MODERATE 0.19 0.341
W03H9.1 WBGene00012227 W03H9.1 II:14149954 protein_coding p.Leu60Phe missense_variant MODERATE 0.181 0.341
daf-5 WBGene00000901 W01G7.1 II:14035732 protein_coding p.Glu209Asp missense_variant MODERATE 0.337 0.337
Y54G11A.4 WBGene00013215 Y54G11A.4 II:14295590 protein_coding p.Leu448Gln missense_variant MODERATE 0.333 0.333
Y53F4B.36 WBGene00013175 Y53F4B.36 II:15176758 protein_coding p.Arg144Cys missense_variant MODERATE 0.323 0.323
Y53F4B.36 WBGene00013175 Y53F4B.36 II:15176480 protein_coding p.Ser66Thr missense_variant MODERATE 0.185 0.323
Y53F4B.36 WBGene00013175 Y53F4B.36 II:15176870 protein_coding p.Val181Ala missense_variant MODERATE 0.185 0.323
Y53F4B.36 WBGene00013175 Y53F4B.36 II:15177264 protein_coding p.Cys296Phe missense_variant MODERATE 0.185 0.323
Y53F4B.62 WBGene00219491 Y53F4B.62a II:15129532 protein_coding p.Ile291Val missense_variant MODERATE 0.318 0.318
Y53F4B.62 WBGene00219491 Y53F4B.62b II:15129532 protein_coding p.Ile37Val missense_variant MODERATE 0.318 0.318
Y53F4B.62 WBGene00219491 Y53F4B.62a II:15129931 protein_coding p.Ile200Phe missense_variant MODERATE 0.318 0.318
Y46E12BR.1 WBGene00021598 Y46E12BR.1 II:15196401 protein_coding p.Gly63Val missense_variant MODERATE 0.318 0.318
spsb-2 WBGene00021596 Y46E12BL.3 II:15232051 protein_coding p.Glu151Ala missense_variant MODERATE 0.318 0.318
Y46E12BL.2 WBGene00021595 Y46E12BL.2a II:15241801 protein_coding p.Gly841Ser missense_variant MODERATE 0.318 0.318
Y53F4B.27 WBGene00013173 Y53F4B.27a II:15150346 protein_coding p.Gly391Arg missense_variant MODERATE 0.318 0.318
Y53F4B.27 WBGene00013173 Y53F4B.27b II:15150346 protein_coding p.Gly283Arg missense_variant MODERATE 0.318 0.318
Y53F4B.20 WBGene00013166 Y53F4B.20 II:15088251 protein_coding p.Asn486Tyr missense_variant MODERATE 0.318 0.318
Y53F4B.18 WBGene00013164 Y53F4B.18 II:15070135 protein_coding p.Ala175Gly missense_variant MODERATE 0.318 0.318
R05H10.3 WBGene00011044 R05H10.3a II:14870979 protein_coding p.Leu83Arg missense_variant MODERATE 0.318 0.318
gst-39 WBGene00001787 Y53F4B.33 II:15171447 protein_coding p.Ile138Val missense_variant MODERATE 0.318 0.318
gst-31 WBGene00001779 Y53F4B.35 II:15174680 protein_coding p.Thr75Ile missense_variant MODERATE 0.318 0.318
asc-1 WBGene00000208 Y53F4B.15 II:15039515 protein_coding p.Gly34Arg missense_variant&splice_region_variant MODERATE 0.318 0.318
asc-1 WBGene00000208 Y53F4B.15 II:15042402 protein_coding p.His221Gln missense_variant MODERATE 0.318 0.318
arrd-14 WBGene00011055 R06B9.4 II:13754632 protein_coding p.Asn193Ser missense_variant MODERATE 0.312 0.312
arrd-14 WBGene00011055 R06B9.4 II:13752462 protein_coding p.Thr48Ile missense_variant MODERATE 0.213 0.312
nep-17 WBGene00010070 F54F11.2a II:13515366 protein_coding p.Arg1431Gly missense_variant MODERATE 0.299 0.299
nep-17 WBGene00010070 F54F11.2b II:13515366 protein_coding p.Arg1302Gly missense_variant MODERATE 0.299 0.299
nep-17 WBGene00010070 F54F11.2a II:13514503 protein_coding p.Gln1292Leu missense_variant MODERATE 0.288 0.299
nep-17 WBGene00010070 F54F11.2b II:13514503 protein_coding p.Gln1163Leu missense_variant MODERATE 0.288 0.299
nep-17 WBGene00010070 F54F11.2a II:13513948 protein_coding p.Gln1107Leu missense_variant MODERATE 0.274 0.299
nep-17 WBGene00010070 F54F11.2a II:13513948 protein_coding p.Gln1107Arg missense_variant MODERATE 0.274 0.299
nep-17 WBGene00010070 F54F11.2b II:13513948 protein_coding p.Gln978Leu missense_variant MODERATE 0.274 0.299
nep-17 WBGene00010070 F54F11.2b II:13513948 protein_coding p.Gln978Arg missense_variant MODERATE 0.274 0.299
nep-17 WBGene00010070 F54F11.2a II:13515486 protein_coding p.Pro1471Ser missense_variant MODERATE 0.253 0.299
nep-17 WBGene00010070 F54F11.2b II:13515486 protein_coding p.Pro1342Ser missense_variant MODERATE 0.253 0.299
nep-17 WBGene00010070 F54F11.2a II:13509611 protein_coding p.His201Asn missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2a II:13509611 protein_coding p.His201Tyr missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2b II:13509611 protein_coding p.His72Asn missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2b II:13509611 protein_coding p.His72Tyr missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2a II:13510451 protein_coding p.Gln383Pro missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2b II:13510451 protein_coding p.Gln254Pro missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2a II:13513396 protein_coding p.Thr923Asn missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2b II:13513396 protein_coding p.Thr794Asn missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2a II:13513524 protein_coding p.Thr966Ala missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2b II:13513524 protein_coding p.Thr837Ala missense_variant MODERATE 0.231 0.299
nep-17 WBGene00010070 F54F11.2a II:13516355 protein_coding p.Gly1586Arg missense_variant MODERATE 0.224 0.299
nep-17 WBGene00010070 F54F11.2a II:13516355 protein_coding p.Gly1586Arg missense_variant MODERATE 0.224 0.299
nep-17 WBGene00010070 F54F11.2b II:13516355 protein_coding p.Gly1457Arg missense_variant MODERATE 0.224 0.299
nep-17 WBGene00010070 F54F11.2b II:13516355 protein_coding p.Gly1457Arg missense_variant MODERATE 0.224 0.299
nep-17 WBGene00010070 F54F11.2a II:13515049 protein_coding p.Val1325Asp missense_variant MODERATE -0.205 0.299
nep-17 WBGene00010070 F54F11.2b II:13515049 protein_coding p.Val1196Asp missense_variant MODERATE -0.205 0.299
nep-17 WBGene00010070 F54F11.2a II:13515433 protein_coding p.Ser1453Asn missense_variant MODERATE -0.205 0.299
nep-17 WBGene00010070 F54F11.2b II:13515433 protein_coding p.Ser1324Asn missense_variant MODERATE -0.205 0.299
nep-17 WBGene00010070 F54F11.2a II:13514095 protein_coding p.Arg1156Ile missense_variant MODERATE 0.194 0.299
nep-17 WBGene00010070 F54F11.2b II:13514095 protein_coding p.Arg1027Ile missense_variant MODERATE 0.194 0.299
nep-17 WBGene00010070 F54F11.2a II:13510054 protein_coding p.Asp332Asn missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13510054 protein_coding p.Asp203Asn missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2a II:13510116 protein_coding p.Leu352Phe missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13510116 protein_coding p.Leu223Phe missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2a II:13510117 protein_coding p.Thr353Ala missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13510117 protein_coding p.Thr224Ala missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2a II:13510459 protein_coding p.Gly386Ser missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13510459 protein_coding p.Gly257Ser missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2a II:13510493 protein_coding p.Lys397Met missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13510493 protein_coding p.Lys268Met missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2a II:13510534 protein_coding p.Leu411Phe missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13510534 protein_coding p.Leu282Phe missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2a II:13513534 protein_coding p.Asp969Gly missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13513534 protein_coding p.Asp840Gly missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2a II:13513548 protein_coding p.Leu974Phe missense_variant MODERATE -0.186 0.299
nep-17 WBGene00010070 F54F11.2b II:13513548 protein_coding p.Leu845Phe missense_variant MODERATE -0.186 0.299
puf-6 WBGene00004242 F18A11.1.1 II:13043171 protein_coding p.Leu57Ser missense_variant MODERATE 0.294 0.294
puf-6 WBGene00004242 F18A11.1.2 II:13043171 protein_coding p.Leu57Ser missense_variant MODERATE 0.294 0.294
puf-6 WBGene00004242 F18A11.1.1 II:13041552 protein_coding p.Leu373Ser missense_variant MODERATE 0.267 0.294
puf-6 WBGene00004242 F18A11.1.2 II:13041552 protein_coding p.Leu373Ser missense_variant MODERATE 0.267 0.294
puf-6 WBGene00004242 F18A11.1.1 II:13043307 protein_coding p.Lys35Arg missense_variant&splice_region_variant MODERATE -0.23 0.294
puf-6 WBGene00004242 F18A11.1.2 II:13043307 protein_coding p.Lys35Arg missense_variant&splice_region_variant MODERATE -0.23 0.294
puf-6 WBGene00004242 F18A11.1.1 II:13043227 protein_coding p.Lys38Asn missense_variant MODERATE 0.213 0.294
puf-6 WBGene00004242 F18A11.1.2 II:13043227 protein_coding p.Lys38Asn missense_variant MODERATE 0.213 0.294
puf-6 WBGene00004242 F18A11.1.1 II:13042887 protein_coding p.Leu152Phe missense_variant MODERATE -0.185 0.294
puf-6 WBGene00004242 F18A11.1.2 II:13042887 protein_coding p.Leu152Phe missense_variant MODERATE -0.185 0.294
btf-1 WBGene00000274 F15D4.1 II:13207424 protein_coding p.Asn738His missense_variant MODERATE 0.294 0.294
btf-1 WBGene00000274 F15D4.1 II:13207426 protein_coding p.Asn738Lys missense_variant MODERATE 0.294 0.294
btf-1 WBGene00000274 F15D4.1 II:13207152 protein_coding p.Thr647Ile missense_variant MODERATE 0.272 0.294
btf-1 WBGene00000274 F15D4.1 II:13208080 protein_coding p.Phe769Leu missense_variant MODERATE 0.25 0.294
btf-1 WBGene00000274 F15D4.1 II:13208080 protein_coding p.Phe769Phe synonymous_variant LOW 0.25 0.294
Y39G8B.5 WBGene00012726 Y39G8B.5 II:13988307 protein_coding p.Asp497Gly missense_variant MODERATE 0.285 0.285
sre-47 WBGene00012725 Y39G8B.4 II:13984380 protein_coding p.Tyr91Phe missense_variant MODERATE 0.285 0.285
sre-43 WBGene00012333 W07G1.6 II:13968559 protein_coding p.Phe129Leu missense_variant MODERATE 0.285 0.285
mltn-5 WBGene00044074 W02B8.6 II:13927609 protein_coding p.Pro139Ser missense_variant MODERATE 0.284 0.284
mltn-5 WBGene00044074 W02B8.6 II:13929265 protein_coding p.Glu548Lys missense_variant MODERATE -0.227 0.284
mltn-5 WBGene00044074 W02B8.6 II:13930163 protein_coding p.Leu622Ile missense_variant MODERATE -0.227 0.284
mltn-5 WBGene00044074 W02B8.6 II:13927619 protein_coding p.Thr142Arg missense_variant MODERATE -0.21 0.284
Y81G3A.4 WBGene00013592 Y81G3A.4a II:13094017 protein_coding p.Glu214Asp missense_variant MODERATE 0.28 0.28
Y81G3A.4 WBGene00013592 Y81G3A.4b II:13094017 protein_coding p.Glu157Asp missense_variant MODERATE 0.28 0.28
W07G1.1 WBGene00012328 W07G1.1 II:13939074 protein_coding p.Pro151Ser missense_variant MODERATE 0.273 0.273
W07G1.1 WBGene00012328 W07G1.1 II:13939022 protein_coding p.Leu168Pro missense_variant MODERATE -0.198 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13659724 protein_coding p.Ser482Pro missense_variant MODERATE 0.273 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661471 protein_coding p.Arg92Lys missense_variant MODERATE 0.257 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661169 protein_coding p.Tyr156Phe missense_variant MODERATE 0.246 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661564 protein_coding p.Pro76Gln missense_variant MODERATE -0.232 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13656009 protein_coding p.Ser892Leu missense_variant MODERATE 0.228 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661145 protein_coding p.Lys164Arg missense_variant MODERATE 0.224 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661175 protein_coding p.Ser154Ile missense_variant MODERATE 0.215 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661109 protein_coding p.Ile176Thr missense_variant MODERATE 0.197 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661119 protein_coding p.Gly173Arg missense_variant MODERATE 0.187 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13661161 protein_coding p.Pro159Ser missense_variant MODERATE 0.181 0.273
C31C9.6 WBGene00007840 C31C9.6 II:13659504 protein_coding p.Ile540Thr missense_variant MODERATE 0.18 0.273
Y54G11A.3 WBGene00013214 Y54G11A.3 II:14281831 protein_coding p.Lys306Asn missense_variant MODERATE -0.27 0.27
Y54G11A.3 WBGene00013214 Y54G11A.3 II:14283588 protein_coding p.Met417Ile missense_variant MODERATE -0.197 0.27
arrd-11 WBGene00011052 R06B9.1 II:13765189 protein_coding p.Ala320Val missense_variant MODERATE 0.269 0.269
arrd-11 WBGene00011052 R06B9.1 II:13764771 protein_coding p.Phe181Val missense_variant MODERATE 0.224 0.269
arrd-11 WBGene00011052 R06B9.1 II:13763597 protein_coding p.Asp57Glu missense_variant MODERATE -0.199 0.269
arrd-13 WBGene00011054 R06B9.3.1 II:13758786 protein_coding p.Arg72Gln missense_variant MODERATE 0.266 0.266
arrd-13 WBGene00011054 R06B9.3.2 II:13758786 protein_coding p.Arg72Gln missense_variant MODERATE 0.266 0.266
hot-3 WBGene00001988 W02B8.5 II:13931975 protein_coding p.Gln8Arg missense_variant MODERATE -0.265 0.265
hot-3 WBGene00001988 W02B8.5 II:13930807 protein_coding p.Met144Ile missense_variant MODERATE -0.21 0.265
K10H10.5 WBGene00010761 K10H10.5 II:14502407 protein_coding p.Gln173Pro missense_variant MODERATE 0.262 0.262
gst-18 WBGene00001766 F37B1.7 II:13630007 protein_coding p.Asp129Gly missense_variant MODERATE -0.254 0.254
gst-18 WBGene00001766 F37B1.7 II:13629941 protein_coding p.Val151Gly missense_variant MODERATE 0.178 0.254
gst-18 WBGene00001766 F37B1.7 II:13629972 protein_coding p.Gly141Arg missense_variant MODERATE 0.178 0.254
mltn-4 WBGene00012200 W02B8.4 II:13924578 protein_coding p.Val686Ile missense_variant MODERATE 0.253 0.253
mltn-4 WBGene00012200 W02B8.4 II:13922816 protein_coding p.Lys363Ile missense_variant MODERATE 0.252 0.253
mltn-4 WBGene00012200 W02B8.4 II:13921631 protein_coding p.Asn136Ser missense_variant MODERATE -0.21 0.253
mltn-4 WBGene00012200 W02B8.4 II:13923132 protein_coding p.Lys451Met missense_variant MODERATE -0.201 0.253
E01G4.6 WBGene00008448 E01G4.6 II:13483436 protein_coding p.Thr309Ala missense_variant MODERATE 0.252 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13483437 protein_coding p.Thr309Lys missense_variant MODERATE 0.252 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13483777 protein_coding p.Phe422Leu missense_variant MODERATE 0.251 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13483793 protein_coding p.Ser428Pro missense_variant MODERATE 0.251 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13484420 protein_coding p.Arg637Gly missense_variant MODERATE 0.251 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13484498 protein_coding p.Ala663Thr missense_variant MODERATE 0.251 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13483700 protein_coding p.Lys397Gln missense_variant MODERATE -0.202 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13484078 protein_coding p.Ser523Thr missense_variant MODERATE -0.202 0.252
E01G4.6 WBGene00008448 E01G4.6 II:13482455 protein_coding p.Val17Ala missense_variant MODERATE 0.185 0.252
Y48E1C.1 WBGene00013014 Y48E1C.1a II:13422646 protein_coding p.Val396Ala missense_variant MODERATE -0.247 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1c II:13422646 protein_coding p.Val145Ala missense_variant MODERATE -0.247 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.1 II:13422646 protein_coding p.Val331Ala missense_variant MODERATE -0.247 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.2 II:13422646 protein_coding p.Val331Ala missense_variant MODERATE -0.247 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.3 II:13422646 protein_coding p.Val331Ala missense_variant MODERATE -0.247 0.247
nan WBGene00013014 nan II:13416559 nan nan nan nan 0.22 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1a II:13420794 protein_coding p.Ala275Val missense_variant MODERATE 0.219 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.1 II:13420794 protein_coding p.Ala210Val missense_variant MODERATE 0.219 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.2 II:13420794 protein_coding p.Ala210Val missense_variant MODERATE 0.219 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.3 II:13420794 protein_coding p.Ala210Val missense_variant MODERATE 0.219 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1a II:13424312 protein_coding p.Leu434Val missense_variant MODERATE -0.18 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1c II:13424312 protein_coding p.Leu183Val missense_variant MODERATE -0.18 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.1 II:13424312 protein_coding p.Leu369Val missense_variant MODERATE -0.18 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.2 II:13424312 protein_coding p.Leu369Val missense_variant MODERATE -0.18 0.247
Y48E1C.1 WBGene00013014 Y48E1C.1d.3 II:13424312 protein_coding p.Leu369Val missense_variant MODERATE -0.18 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13774626 protein_coding p.Ile603Thr missense_variant MODERATE 0.247 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13774626 protein_coding p.Ile533Thr missense_variant MODERATE 0.247 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13776406 protein_coding p.Ile957Val missense_variant MODERATE 0.241 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13776406 protein_coding p.Ile887Val missense_variant MODERATE 0.241 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13777593 protein_coding p.Ala1292Thr missense_variant MODERATE 0.241 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13777593 protein_coding p.Ala1222Thr missense_variant MODERATE 0.241 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13778580 protein_coding p.Asn1551His missense_variant MODERATE 0.241 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13778580 protein_coding p.Asn1481His missense_variant MODERATE 0.241 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13772444 protein_coding p.Tyr73Phe missense_variant MODERATE -0.231 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13772444 protein_coding p.Tyr3Phe missense_variant MODERATE -0.231 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13778157 protein_coding p.Asn1410Tyr missense_variant MODERATE -0.209 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13778157 protein_coding p.Asn1340Tyr missense_variant MODERATE -0.209 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13774915 protein_coding p.Pro683Ser missense_variant MODERATE 0.198 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13774915 protein_coding p.Pro613Ser missense_variant MODERATE 0.198 0.247
C01B9.1 WBGene00007220 C01B9.1b II:13774131 protein_coding p.Phe454Cys missense_variant MODERATE 0.184 0.247
C01B9.1 WBGene00007220 C01B9.1a II:13774131 protein_coding p.Phe384Cys missense_variant MODERATE 0.184 0.247
W07G1.5 WBGene00012332 W07G1.5b II:13959273 protein_coding p.Glu440Gly missense_variant MODERATE 0.243 0.243
W07G1.5 WBGene00012332 W07G1.5a II:13959273 protein_coding p.Glu428Gly missense_variant MODERATE 0.243 0.243
Y48E1C.2 WBGene00013015 Y48E1C.2.1 II:13427617 protein_coding p.Asn241His missense_variant MODERATE 0.243 0.243
Y48E1C.2 WBGene00013015 Y48E1C.2.2 II:13427617 protein_coding p.Asn241His missense_variant MODERATE 0.243 0.243
Y48E1C.2 WBGene00013015 Y48E1C.2.1 II:13427665 protein_coding p.Val257Ile missense_variant MODERATE 0.243 0.243
Y48E1C.2 WBGene00013015 Y48E1C.2.2 II:13427665 protein_coding p.Val257Ile missense_variant MODERATE 0.243 0.243
gst-17 WBGene00001765 F37B1.6 II:13628084 protein_coding p.Ala167Val missense_variant MODERATE -0.242 0.242
gst-17 WBGene00001765 F37B1.6 II:13628517 protein_coding p.Pro23Ser missense_variant MODERATE 0.239 0.242
gst-17 WBGene00001765 F37B1.6 II:13628315 protein_coding p.Ser90Cys missense_variant MODERATE 0.178 0.242
F42G4.2 WBGene00009641 F42G4.2 II:13048499 protein_coding p.Asp72Asn missense_variant MODERATE 0.241 0.241
fbxa-167 WBGene00007837 C31C9.3 II:13643688 protein_coding p.Met366Ile missense_variant MODERATE -0.241 0.241
C31C9.2 WBGene00007836 C31C9.2 II:13637156 protein_coding p.Ile303Phe missense_variant MODERATE -0.241 0.241
pqn-27 WBGene00004116 E01G4.4a II:13449529 protein_coding p.Lys515Asn missense_variant MODERATE -0.239 0.239
pqn-27 WBGene00004116 E01G4.4c.4 II:13449529 protein_coding p.Lys354Asn missense_variant MODERATE -0.239 0.239
pqn-27 WBGene00004116 E01G4.4c.3 II:13449529 protein_coding p.Lys354Asn missense_variant MODERATE -0.239 0.239
pqn-27 WBGene00004116 E01G4.4c.2 II:13449529 protein_coding p.Lys354Asn missense_variant MODERATE -0.239 0.239
pqn-27 WBGene00004116 E01G4.4b II:13449529 protein_coding p.Lys452Asn missense_variant MODERATE -0.239 0.239
pqn-27 WBGene00004116 E01G4.4c.1 II:13449529 protein_coding p.Lys354Asn missense_variant MODERATE -0.239 0.239
mig-14 WBGene00003246 R06B9.6 II:13746322 protein_coding p.Val285Ala missense_variant MODERATE 0.238 0.238
mig-14 WBGene00003246 R06B9.6 II:13744105 protein_coding p.Arg138His missense_variant MODERATE 0.224 0.238
Y38F1A.1 WBGene00012605 Y38F1A.1 II:12953050 protein_coding p.Thr138Lys missense_variant MODERATE -0.232 0.232
Y38F1A.1 WBGene00012605 Y38F1A.1 II:12952778 protein_coding p.Phe212Ser missense_variant MODERATE 0.209 0.232
Y38F1A.1 WBGene00012605 Y38F1A.1 II:12953039 protein_coding p.Ser142Thr missense_variant MODERATE -0.199 0.232
Y38F1A.1 WBGene00012605 Y38F1A.1 II:12953039 protein_coding p.Ser142Pro missense_variant MODERATE -0.199 0.232
Y38F1A.1 WBGene00012605 Y38F1A.1 II:12952923 protein_coding p.Ser164Ala missense_variant MODERATE 0.195 0.232
gst-24 WBGene00001772 F37B1.1 II:13610488 protein_coding p.Val208Ile missense_variant MODERATE -0.232 0.232
arrd-12 WBGene00011053 R06B9.2b II:13767434 protein_coding p.Ser137Thr missense_variant MODERATE 0.231 0.231
arrd-12 WBGene00011053 R06B9.2a II:13767434 protein_coding p.Ser137Thr missense_variant MODERATE 0.231 0.231
eat-2 WBGene00001133 Y48B6A.4 II:14171477 protein_coding p.Leu3Ser missense_variant MODERATE 0.229 0.229
cyd-1 WBGene00000870 Y38F1A.5.1 II:12988631 protein_coding p.Ser39Thr missense_variant&splice_region_variant MODERATE 0.224 0.224
cyd-1 WBGene00000870 Y38F1A.5.1 II:12988631 protein_coding p.Ser39Pro missense_variant&splice_region_variant MODERATE 0.224 0.224
cyd-1 WBGene00000870 Y38F1A.5.2 II:12988631 protein_coding p.Ser39Thr missense_variant&splice_region_variant MODERATE 0.224 0.224
cyd-1 WBGene00000870 Y38F1A.5.2 II:12988631 protein_coding p.Ser39Pro missense_variant&splice_region_variant MODERATE 0.224 0.224
cyd-1 WBGene00000870 Y38F1A.5.1 II:12988925 protein_coding p.Met137Leu missense_variant MODERATE 0.224 0.224
cyd-1 WBGene00000870 Y38F1A.5.2 II:12988925 protein_coding p.Met137Leu missense_variant MODERATE 0.224 0.224
ZK131.11 WBGene00013934 ZK131.11b II:13803205 protein_coding p.Asn116Tyr missense_variant MODERATE 0.224 0.224
bub-3 WBGene00013209 Y54G9A.6 II:13728035 protein_coding p.Val211Leu missense_variant MODERATE 0.224 0.224
F08G2.8 WBGene00008579 F08G2.8 II:13855185 protein_coding p.Phe226Val missense_variant MODERATE 0.224 0.224
F08G2.7 WBGene00008578 F08G2.7 II:13838372 protein_coding p.Asn199Thr missense_variant MODERATE 0.224 0.224
F08G2.7 WBGene00008578 F08G2.7 II:13838601 protein_coding p.Ser123Pro missense_variant MODERATE -0.209 0.224
F08G2.7 WBGene00008578 F08G2.7 II:13838685 protein_coding p.Phe95Ile missense_variant MODERATE -0.209 0.224
sam-10 WBGene00012990 Y48C3A.8a.1 II:13325402 protein_coding p.Thr298Ala missense_variant MODERATE 0.223 0.223
sam-10 WBGene00012990 Y48C3A.8a.2 II:13325402 protein_coding p.Thr298Ala missense_variant MODERATE 0.223 0.223
sam-10 WBGene00012990 Y48C3A.8b II:13325402 protein_coding p.Thr94Ala missense_variant MODERATE 0.223 0.223
csp-1 WBGene00000819 Y48E1B.13a II:13604502 protein_coding p.Cys406Tyr missense_variant MODERATE -0.223 0.223
csp-1 WBGene00000819 Y48E1B.13c II:13604502 protein_coding p.Cys138Tyr missense_variant MODERATE -0.223 0.223
csp-1 WBGene00000819 Y48E1B.13b II:13604502 protein_coding p.Cys138Tyr missense_variant MODERATE -0.223 0.223
Y48C3A.14 WBGene00012995 Y48C3A.14a II:13401735 protein_coding p.Arg844Lys missense_variant MODERATE -0.222 0.222
Y48C3A.14 WBGene00012995 Y48C3A.14c II:13401735 protein_coding p.Arg708Lys missense_variant MODERATE -0.222 0.222
Y48C3A.14 WBGene00012995 Y48C3A.14b II:13401735 protein_coding p.Arg339Lys missense_variant MODERATE -0.222 0.222
Y48C3A.14 WBGene00012995 Y48C3A.14d II:13401735 protein_coding p.Arg138Lys missense_variant MODERATE -0.222 0.222
snx-14 WBGene00013011 Y48E1B.14a.1 II:13530983 protein_coding p.Phe51Leu missense_variant MODERATE -0.222 0.222
snx-14 WBGene00013011 Y48E1B.14a.2 II:13530983 protein_coding p.Phe51Leu missense_variant MODERATE -0.222 0.222
snx-14 WBGene00013011 Y48E1B.14b II:13530983 protein_coding p.Phe50Leu missense_variant MODERATE -0.222 0.222
snx-14 WBGene00013011 Y48E1B.14a.1 II:13527360 protein_coding p.Pro573Ala missense_variant MODERATE -0.213 0.222
snx-14 WBGene00013011 Y48E1B.14a.2 II:13527360 protein_coding p.Pro573Ala missense_variant MODERATE -0.213 0.222
F42G4.7 WBGene00009644 F42G4.7 II:13047114 protein_coding p.Tyr33Asp missense_variant MODERATE 0.221 0.221
Y53F4B.19 WBGene00013165 Y53F4B.19 II:15077463 protein_coding p.Ser64Leu missense_variant&splice_region_variant MODERATE -0.219 0.219
Y81G3A.1 WBGene00013590 Y81G3A.1 II:13083541 protein_coding p.Phe28Cys missense_variant MODERATE 0.218 0.218
efhd-1 WBGene00012980 Y48B6A.6a.1 II:14181594 protein_coding p.Gln186Pro missense_variant MODERATE 0.217 0.217
efhd-1 WBGene00012980 Y48B6A.6a.2 II:14181594 protein_coding p.Gln186Pro missense_variant MODERATE 0.217 0.217
efhd-1 WBGene00012980 Y48B6A.6a.1 II:14181303 protein_coding p.Arg89Pro missense_variant MODERATE 0.199 0.217
efhd-1 WBGene00012980 Y48B6A.6a.2 II:14181303 protein_coding p.Arg89Pro missense_variant MODERATE 0.199 0.217
efhd-1 WBGene00012980 Y48B6A.6a.1 II:14181559 protein_coding p.Lys174Asn missense_variant MODERATE -0.192 0.217
efhd-1 WBGene00012980 Y48B6A.6a.2 II:14181559 protein_coding p.Lys174Asn missense_variant MODERATE -0.192 0.217
efhd-1 WBGene00012980 Y48B6A.6a.1 II:14187952 protein_coding p.Gly548Asp missense_variant MODERATE 0.185 0.217
efhd-1 WBGene00012980 Y48B6A.6a.2 II:14187952 protein_coding p.Gly548Asp missense_variant MODERATE 0.185 0.217
efhd-1 WBGene00012980 Y48B6A.6b II:14187952 protein_coding p.Gly64Asp missense_variant MODERATE 0.185 0.217
efhd-1 WBGene00012980 Y48B6A.6c II:14187952 protein_coding p.Gly40Asp missense_variant MODERATE 0.185 0.217
Y48E1B.3 WBGene00013002 Y48E1B.3c II:13553244 protein_coding p.Thr670Ala missense_variant MODERATE 0.215 0.215
Y48E1B.3 WBGene00013002 Y48E1B.3a.2 II:13553244 protein_coding p.Thr147Ala missense_variant MODERATE 0.215 0.215
Y48E1B.3 WBGene00013002 Y48E1B.3d II:13553244 protein_coding p.Thr503Ala missense_variant MODERATE 0.215 0.215
Y48E1B.3 WBGene00013002 Y48E1B.3a.1 II:13553244 protein_coding p.Thr147Ala missense_variant MODERATE 0.215 0.215
ctl-2 WBGene00000831 Y54G11A.5.1 II:14301272 protein_coding p.Ile226Thr missense_variant MODERATE -0.214 0.214
ctl-2 WBGene00000831 Y54G11A.5.2 II:14301272 protein_coding p.Ile226Thr missense_variant MODERATE -0.214 0.214
W02B8.1 WBGene00012197 W02B8.1.1 II:13900606 protein_coding p.Ile34Val missense_variant MODERATE 0.213 0.213
W02B8.1 WBGene00012197 W02B8.1.2 II:13900606 protein_coding p.Ile34Val missense_variant MODERATE 0.213 0.213
gfm-1 WBGene00009246 F29C12.4.1 II:13118413 protein_coding p.Gln270Glu missense_variant MODERATE 0.211 0.211
gfm-1 WBGene00009246 F29C12.4.2 II:13118413 protein_coding p.Gln270Glu missense_variant MODERATE 0.211 0.211
hda-10 WBGene00001838 Y51H1A.5 II:13882737 protein_coding p.Val9Met missense_variant MODERATE -0.211 0.211
hda-10 WBGene00001838 Y51H1A.5 II:13885045 protein_coding p.Ile197Phe missense_variant MODERATE -0.181 0.211
mltn-10 WBGene00008965 F19H8.5 II:14624609 protein_coding p.Glu239Asp missense_variant&splice_region_variant MODERATE -0.21 0.21
mltn-3 WBGene00012199 W02B8.3 II:13918151 protein_coding p.Asn421Thr missense_variant MODERATE -0.21 0.21
F01D5.10 WBGene00008500 F01D5.10 II:14020900 protein_coding p.Pro16Ala missense_variant MODERATE -0.21 0.21
sre-45 WBGene00010071 F54F11.3 II:13519520 protein_coding p.Phe200Leu missense_variant MODERATE 0.21 0.21
F15D4.4 WBGene00008861 F15D4.4 II:13239622 protein_coding p.Lys515Glu missense_variant MODERATE 0.209 0.209
Y46G5A.29 WBGene00012917 Y46G5A.29 II:12858994 protein_coding p.Arg475Ser missense_variant MODERATE 0.209 0.209
Y38F1A.7 WBGene00012609 Y38F1A.7 II:12997238 protein_coding p.Asp86Asn missense_variant MODERATE 0.209 0.209
Y38F1A.4 WBGene00012607 Y38F1A.4 II:12967005 protein_coding p.Lys299Arg missense_variant MODERATE 0.209 0.209
F58G1.7 WBGene00010269 F58G1.7 II:12944307 protein_coding p.Ser534Ile missense_variant MODERATE 0.209 0.209
F58G1.7 WBGene00010269 F58G1.7 II:12944307 protein_coding p.Ser534Thr missense_variant MODERATE 0.209 0.209
F58G1.2 WBGene00010264 F58G1.2b II:12918624 protein_coding p.Ala64Val missense_variant MODERATE 0.209 0.209
F58G1.2 WBGene00010264 F58G1.2a.3 II:12918624 protein_coding p.Ala9Val missense_variant MODERATE 0.209 0.209
F58G1.2 WBGene00010264 F58G1.2a.2 II:12918624 protein_coding p.Ala9Val missense_variant MODERATE 0.209 0.209
F58G1.2 WBGene00010264 F58G1.2a.1 II:12918624 protein_coding p.Ala9Val missense_variant MODERATE 0.209 0.209
wago-4 WBGene00010263 F58G1.1 II:12922174 protein_coding p.His743Arg missense_variant MODERATE 0.209 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902031 protein_coding p.Ser182Cys missense_variant MODERATE 0.209 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902031 protein_coding p.Ser182Cys missense_variant MODERATE 0.209 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12901772 protein_coding p.Ser113Thr missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12901772 protein_coding p.Ser113Thr missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12901773 protein_coding p.Ser113Arg missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12901773 protein_coding p.Ser113Arg missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12901777 protein_coding p.Pro115Ser missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12901777 protein_coding p.Pro115Ser missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902000 protein_coding p.Pro172Ser missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902000 protein_coding p.Pro172Ser missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902347 protein_coding p.Phe219Tyr missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902347 protein_coding p.Phe219Tyr missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902356 protein_coding p.Gln222Arg missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902356 protein_coding p.Gln222Arg missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902400 protein_coding p.Arg237Cys missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902400 protein_coding p.Arg237Cys missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902461 protein_coding p.Ser257Thr missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902461 protein_coding p.Ser257Thr missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902535 protein_coding p.Asn282His missense_variant&splice_region_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902535 protein_coding p.Asn282His missense_variant&splice_region_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.1 II:12902939 protein_coding p.Thr289Ser missense_variant MODERATE 0.195 0.209
clec-65 WBGene00009396 F35C5.8.2 II:12902939 protein_coding p.Thr289Ser missense_variant MODERATE 0.195 0.209
K09E4.4 WBGene00010722 K09E4.4.1 II:14115674 protein_coding p.Gly435Ser missense_variant MODERATE -0.209 0.209
K09E4.4 WBGene00010722 K09E4.4.2 II:14115674 protein_coding p.Gly435Ser missense_variant MODERATE -0.209 0.209
K09E4.4 WBGene00010722 K09E4.4.1 II:14118043 protein_coding p.Arg21Ser missense_variant MODERATE -0.199 0.209
K09E4.4 WBGene00010722 K09E4.4.2 II:14118043 protein_coding p.Arg21Ser missense_variant MODERATE -0.199 0.209
K09E4.4 WBGene00010722 K09E4.4.1 II:14115440 protein_coding p.Pro513Ser missense_variant MODERATE -0.192 0.209
K09E4.4 WBGene00010722 K09E4.4.2 II:14115440 protein_coding p.Pro513Ser missense_variant MODERATE -0.192 0.209
Y51H1A.2 WBGene00013093 Y51H1A.2a II:13865992 protein_coding p.Val399Ile missense_variant MODERATE -0.209 0.209
Y51H1A.2 WBGene00013093 Y51H1A.2b II:13865992 protein_coding p.Val389Ile missense_variant MODERATE -0.209 0.209
lin-38 WBGene00013006 Y48E1B.7 II:13576012 protein_coding p.Asp10Glu missense_variant&splice_region_variant MODERATE -0.208 0.208
F54F11.1 WBGene00010069 F54F11.1 II:13505346 protein_coding p.Asp180Glu missense_variant MODERATE 0.205 0.205
xrn-1 WBGene00012730 Y39G8C.1.1 II:14075065 protein_coding p.Ala404Val missense_variant MODERATE 0.204 0.204
xrn-1 WBGene00012730 Y39G8C.1.2 II:14075065 protein_coding p.Ala404Val missense_variant MODERATE 0.204 0.204
ins-37 WBGene00002120 F08G2.6 II:13835624 protein_coding p.Met13Lys missense_variant MODERATE 0.203 0.203
C09F9.2 WBGene00007479 C09F9.2 II:14711103 protein_coding p.His1327Tyr missense_variant MODERATE -0.203 0.203
F15D4.5 WBGene00008862 F15D4.5 II:13247398 protein_coding p.Cys427Trp missense_variant MODERATE 0.2 0.2
xrn-2 WBGene00006964 Y48B6A.3 II:14165377 protein_coding p.Leu797Val missense_variant MODERATE 0.199 0.199
xrn-2 WBGene00006964 Y48B6A.3 II:14157980 protein_coding p.Pro319Gln missense_variant MODERATE 0.181 0.199
xrn-2 WBGene00006964 Y48B6A.3 II:14164257 protein_coding p.Val638Glu missense_variant MODERATE 0.181 0.199
bath-45 WBGene00009247 F29C12.5 II:13123490 protein_coding p.Lys134Asn missense_variant MODERATE -0.197 0.197
Y54G11A.7 WBGene00013216 Y54G11A.7 II:14298345 protein_coding p.Gln208His missense_variant MODERATE -0.197 0.197
clec-66 WBGene00009397 F35C5.9 II:12904764 protein_coding p.Thr96Ser missense_variant MODERATE 0.195 0.195
cacn-1 WBGene00012230 W03H9.4a.1 II:14136464 protein_coding p.Glu390Lys missense_variant MODERATE -0.192 0.192
cacn-1 WBGene00012230 W03H9.4b II:14136464 protein_coding p.Glu78Lys missense_variant MODERATE -0.192 0.192
cacn-1 WBGene00012230 W03H9.4a.2 II:14136464 protein_coding p.Glu390Lys missense_variant MODERATE -0.192 0.192
agl-1 WBGene00011050 R06A4.8.1 II:14353324 protein_coding p.Glu977Asp missense_variant MODERATE -0.19 0.19
agl-1 WBGene00011050 R06A4.8.2 II:14353324 protein_coding p.Glu977Asp missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2a II:14396081 protein_coding p.Ser853Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2i II:14396081 protein_coding p.Ser853Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2k II:14396081 protein_coding p.Ser853Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2b II:14396081 protein_coding p.Ser853Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2c II:14396081 protein_coding p.Ser853Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2n II:14396081 protein_coding p.Ser853Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2l II:14396081 protein_coding p.Ser732Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2m II:14396081 protein_coding p.Ser732Cys missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2a II:14398761 protein_coding p.Thr1165Ala missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2i II:14398761 protein_coding p.Thr1165Ala missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2k II:14398761 protein_coding p.Thr1167Ala missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2b II:14398761 protein_coding p.Thr1165Ala missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2c II:14398761 protein_coding p.Thr1165Ala missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2n II:14398761 protein_coding p.Thr1167Ala missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2l II:14398761 protein_coding p.Thr1046Ala missense_variant MODERATE -0.19 0.19
nurf-1 WBGene00009180 F26H11.2m II:14398761 protein_coding p.Thr1044Ala missense_variant MODERATE -0.19 0.19
plx-2 WBGene00004048 K04B12.1 II:14422568 protein_coding p.Gly580Ser missense_variant MODERATE -0.19 0.19
plx-2 WBGene00004048 K04B12.1 II:14422769 protein_coding p.His513Asn missense_variant MODERATE -0.19 0.19
mes-2 WBGene00003220 R06A4.7 II:14384362 protein_coding p.Glu129Asp missense_variant MODERATE -0.19 0.19
ztf-22 WBGene00012988 Y48C3A.4 II:13283052 protein_coding p.Pro94Leu missense_variant MODERATE -0.189 0.189
rict-1 WBGene00009245 F29C12.3b II:13102810 protein_coding p.His1214Tyr missense_variant MODERATE -0.189 0.189
rict-1 WBGene00009245 F29C12.3c II:13102810 protein_coding p.His402Tyr missense_variant MODERATE -0.189 0.189
rict-1 WBGene00009245 F29C12.3a II:13102810 protein_coding p.His1212Tyr missense_variant MODERATE -0.189 0.189
ace-3 WBGene00000037 Y48B6A.8 II:14205818 protein_coding p.Pro27Gln missense_variant MODERATE 0.188 0.188
clec-64 WBGene00009395 F35C5.7 II:12899533 protein_coding p.Asp158Asn missense_variant MODERATE 0.188 0.188
csc-1 WBGene00000804 Y48E1B.12 II:13597183 protein_coding p.Asp59Asn missense_variant MODERATE -0.187 0.187
col-86 WBGene00000661 Y81G3A.5a II:13096421 protein_coding p.Ala206Glu missense_variant MODERATE 0.186 0.186
col-86 WBGene00000661 Y81G3A.5b II:13096421 protein_coding p.Ala61Glu missense_variant MODERATE 0.186 0.186
col-86 WBGene00000661 Y81G3A.5a II:13096416 protein_coding p.Val208Phe missense_variant MODERATE 0.186 0.186
col-86 WBGene00000661 Y81G3A.5b II:13096416 protein_coding p.Val63Phe missense_variant MODERATE 0.186 0.186
nan WBGene00008444 nan II:13443190 nan nan nan nan -0.186 0.186
F32A11.1 WBGene00009307 F32A11.1.1 II:13157807 protein_coding p.Thr117Ala missense_variant MODERATE 0.186 0.186
F32A11.1 WBGene00009307 F32A11.1.2 II:13157807 protein_coding p.Thr117Ala missense_variant MODERATE 0.186 0.186
Y81G3A.6 WBGene00195150 Y81G3A.6 II:13081812 protein_coding p.Ser129Gly missense_variant MODERATE 0.185 0.185
hhat-1 WBGene00013852 ZC101.3 II:14678541 protein_coding p.Glu7Lys missense_variant MODERATE 0.185 0.185
cysl-2 WBGene00010759 K10H10.2.1 II:14494335 protein_coding p.Leu29Ile missense_variant MODERATE -0.184 0.184
cysl-2 WBGene00010759 K10H10.2.2 II:14494335 protein_coding p.Leu29Ile missense_variant MODERATE -0.184 0.184
F57C2.4 WBGene00010196 F57C2.4 II:14525882 protein_coding p.Asp56Asn missense_variant MODERATE -0.184 0.184
Y48C3A.5 WBGene00012989 Y48C3A.5b II:13304020 protein_coding p.Val648Ala missense_variant MODERATE 0.183 0.183
Y48C3A.5 WBGene00012989 Y48C3A.5a II:13304020 protein_coding p.Val565Ala missense_variant MODERATE 0.183 0.183
Y48C3A.5 WBGene00012989 Y48C3A.5c II:13304020 protein_coding p.Val340Ala missense_variant MODERATE 0.183 0.183
gst-16 WBGene00001764 F37B1.5 II:13623199 protein_coding p.Asp154Gly missense_variant MODERATE 0.182 0.182
nlp-41 WBGene00007316 C04H5.8b II:14552363 protein_coding p.Leu23His missense_variant MODERATE -0.182 0.182
nlp-41 WBGene00007316 C04H5.8a II:14552363 protein_coding p.Pro68Pro synonymous_variant LOW -0.182 0.182
mrpl-37 WBGene00013004 Y48E1B.5 II:13571868 protein_coding p.Gln297Glu missense_variant MODERATE -0.181 0.181
Y48C3A.12 WBGene00012994 Y48C3A.12 II:13379281 protein_coding p.Thr115Ser missense_variant MODERATE 0.181 0.181
Y48B6A.13 WBGene00012984 Y48B6A.13b.1 II:14226069 protein_coding p.Thr64Met missense_variant&splice_region_variant MODERATE 0.181 0.181
Y48B6A.13 WBGene00012984 Y48B6A.13b.2 II:14226069 protein_coding p.Thr64Met missense_variant&splice_region_variant MODERATE 0.181 0.181
cyp-37A1 WBGene00008499 F01D5.9.1 II:14016039 protein_coding p.Pro183Ser missense_variant MODERATE 0.181 0.181
cyp-37A1 WBGene00008499 F01D5.9.2 II:14016039 protein_coding p.Pro183Ser missense_variant MODERATE 0.181 0.181
F01D5.7 WBGene00008497 F01D5.7b II:14009128 protein_coding p.Arg41Trp missense_variant MODERATE 0.181 0.181
F01D5.7 WBGene00008497 F01D5.7a II:14009128 protein_coding p.Arg41Trp missense_variant MODERATE 0.181 0.181
W01D2.3 WBGene00012180 W01D2.3a II:14804073 protein_coding p.Thr42Met missense_variant MODERATE -0.179 0.179
W01D2.3 WBGene00012180 W01D2.3b.2 II:14804073 protein_coding nan 5_prime_UTR_premature_start_codon_gain_variant LOW -0.179 0.179
W01D2.3 WBGene00012180 W01D2.3b.1 II:14804073 protein_coding nan 5_prime_UTR_premature_start_codon_gain_variant LOW -0.179 0.179
R05H10.7 WBGene00011046 R05H10.7 II:14856804 protein_coding p.Glu179Ala missense_variant MODERATE -0.179 0.179
cdh-7 WBGene00000399 R05H10.6 II:14846047 protein_coding p.Gly253Asp missense_variant MODERATE -0.179 0.179
cdh-7 WBGene00000399 R05H10.6 II:14850114 protein_coding p.Leu1258Phe missense_variant MODERATE -0.179 0.179
his-42 WBGene00001916 F08G2.3 II:13828463 protein_coding p.Phe79Leu missense_variant MODERATE -0.178 0.178

Global Distribution

Isotypes that were included in this trait mapping are opaque/solid. Translucent markers represent isotypes that were not submitted in this trait mapping.
Reference () Alternative ()

Reference

Variant

Tajima's D

Tajima's D is plotted across the most significant QTL genomic region of interest. Tajima's D suggests if a genomic region has an excess or paucity of rare variation. Values close to zero indicate that variation is drifting and not selected. Values less than zero suggest that rare variants are present, which could have arose during a selective sweep, population expansion after a bottleneck, or linkage to a swept allele. Values greater than zero suggest that balancing selection could have occurred or recent population contractions.




1.2.9